Hi, I have a question about the difference between

1: Targeting a driver using Port Audio
2: Selecting an interface in Jack Control

This is the situation. 

I have PortAudio setup to target ASIO4ALL: 
"C:\Program Files\Jack\jackd.exe" -R -S -d portaudio -d "ASIO::ASIO4ALL v2" -r48000 -p512"

What I really want to do is target Dante: 
"C:\Program Files\Jack\jackd.exe" -R -S -d portaudio -d "ASIO::Dante Virtual Soundcard (x64)" r48000 -p512"

When I try this, i get the following error: 

So, I tried thhe following. 
I left my PortAudio to target ASIO4ALL

And in Jack Control I selected Dante as an output under advanced settings. 

No errors this time. 

So what is the difference between "targeting a driver" and selecting a default IO? 

Thanks in advance. 

Marijn