Niels was all like: 
 Any dev's here implement a loosely decoupled frontend/backed like this before and run into issues i with it?

Implemented a GUI / Engine style program with OSC inbetween: Yup. C++ & LibLO & GTKmm
Run into issues with it: Nope. 

There have been some minor OSC issues, but I'm confident that they're my misuse of the libLO.. :-) 

If your intrested the sources of the implementation are available here:
http://github.com/harryhaaren/Luppp

Cheerio, -H

PS: Although the project is in some working state, its really is a WIP. The OSC code is pretty OK i think,
but there are some bad decisions made with regard to classes and "static" data attributes. Keep that in mind..