OK.....

Friend sends rough mix of drums and bass in mp3 form.

Tells me to record new guitars to this.....(he expects a wav file in return).

This "master in mp3 form" makes me a bit nervous.  Why?

Because I don't know enough about the mp3 encoding process.........

Is it "lossy" simply because it rounds-off stuff? 

Or does it actually drop samples (like various lossy video encoders?)

If so, the wav file that I send him could get weird sample-wise when he imports it into the "real" session, no?

Am I picking nits here?