No, it&#39;s not possible. I&#39;ve tried Reason, Ableton, Cubase, all the shizznit. Nothing works via Wine or Virtualization. Technically, even if it does, there&#39;ll be a huge latency issue. And by works, I mean from sequence to synthesis to dac, not &quot;program starts up ok&quot;. If VMWare has proper JACK output, then it might. The problem is virtualization virtualizes a sound chip, often one just adequate to play back system sounds or at most music.<br>