The 100 Hz
(being 2x 50Hz, the power freq. in Italy)
suggests that it is probably related to some manner of
power supply. However, I have no theory why we're
getting 2x 50Hz (and I think I need one :-)).
The implication has been that the USB audio device is a cheaper device. It is therefore
more likely that the device runs from the USB 5 volt line than have a separate power
supply, and that 5v line is regulated and therefore less likely to have a power line
ripple on it.