[LAU] What professional PCIe audio cards do work with Linux?

Hi :) I already asked on some lists about my RME HDSPe AIO card. I explicitly bought this for Linux usage only in 2011, but never needed all available channels until now. Now I notice that the card can't be used for serious audio productions. At the moment I'm producing. It's very time consuming and a lot of the things I need aren't available. The card + ADAT comes with 10 IOs, but only 4 can be used, so I only can loop in one 19" reverb, already a help, but not enough for my needs. Are there any professional PCIe audio cards that are working with Linux? I'll ask this on several lists, perhaps somebody does know such a card at least on one list. Regards, Ralf