I'm hoping I'll be able to find someone else with a similar setup that has overcome their problems to get realtime operation, at least in one direction, with no xruns. Setup: Dell M90 (intel-hda audio) Kernel 2.6.24 RT PREMPT SMP from gentoo pro-audio feed quadro 1500fx with nvidia driver (i'd really like to keep this driver, unless compiz works now with the nv driver) I've tried multiple combinations of: irqpoll noacpi noapic pci=biosirq, some combinations help to reduce latency, but not enough to be useable I have GNX4 Guitar interface that works as a usb device, its almost useable with the same settings the intel-hda card skips with. I have an Opteron with sb-live that no no latency problems, and the GNX4 works great with it. What suggestions for Frames/Period, Sample Rate, Periods/Buffer would people reccomend to make this useable. I really just want to be able to mix and output audio in realtime on my laptop with its intel-hda card, full duples with the GNX4 on it would be an added bonus. If anyone is willing to look over the kernel config I can send them It, didn't want to clutter the list with it now. cat /proc/interrupts CPU0 CPU1 0: 20489426 0 XT-PIC-XT timer 1: 14552 0 XT-PIC-XT i8042 2: 0 0 XT-PIC-XT cascade 5: 0 0 XT-PIC-XT uhci_hcd:usb4 7: 2008 0 XT-PIC-XT ipw3945 8: 2 0 XT-PIC-XT rtc 9: 2930465 0 XT-PIC-XT acpi, uhci_hcd:usb3, nvidia 10: 269 0 XT-PIC-XT uhci_hcd:usb1, ehci_hcd:usb5 11: 1627576 0 XT-PIC-XT uhci_hcd:usb2, HDA Intel 12: 16281 0 XT-PIC-XT i8042 14: 60131 0 XT-PIC-XT libata 15: 64207 0 XT-PIC-XT libata 218: 1624641 0 PCI-MSI-edge eth0 NMI: 0 0 Non-maskable interrupts LOC: 5672972 14563710 Local timer interrupts RES: 9766464 13228888 Rescheduling interrupts CAL: 46404 41727 function call interrupts TLB: 21123 35433 TLB shootdowns TRM: 0 0 Thermal event interrupts SPU: 0 0 Spurious interrupts ERR: 0 MIS: 0 Thanks in advance, Nathanael